Cascade-crRNA complex production service
Design of crRNA for CRISPR-Cas3 genome editing and service for the production of crRNA and Cas protein complexes.
This service provides the design of crRNA (guide RNA) for CRISPR-Cas3 genome editing and the production of a complex of crRNA and Cas proteins (Cas complex for antiviral defense, Cascade-crRNA complex). We co-express five types of proteins that make up the Cascade and one type of crRNA, and deliver the purified Cascade-crRNA complex. Additionally, the proteins that constitute the Cascade (Cas11, Cas7, Cas6) have nuclear localization signals (NLS). By combining the Cascade-crRNA complex produced by this service with the separately sold Cas3 protein NLS that has cleavage activity, it can be utilized in the new genome editing technology "CRISPR-Cas3 system" developed in Japan. *For more details, please refer to the catalog.
- Company：ニッポンジーン
- Price：Other
